Panama
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Start your own vacation rental business in Panama
Where cosmopolitan energy meets tropical rainforests, Panama offers a one-of-a-kind blend of modern living, natural beauty, and rich culture—making it the perfect place to launch a profitable vacation rental business. From beachfront hideaways and city-view condos to jungle retreats and canal-side villas, travelers are looking for short-term vacation rentals that offer more than a place to sleep—they want an experience. That’s where Casiola comes in—our proven franchise model gives you everything you need to build a successful, fully managed short-term rental brand in this dynamic Central American destination. Get your free franchise market analysis for Panama.
Interested? Call us today at 1-800-486-6650 or email us at [email protected]
Russ – Director of Franchise

Becoming a Casiola franchisee is a game-changing opportunity
Make more,
save more
Make more money with our award-winning marketing and revenue management, and save on expenses with our technology, automation, and buying power.
Grow your business faster
Add more homes to your inventory quickly with our proven owner-acquisition platform and business development processes.
Create Work/Life balance
Achieve a more fulfilling work and personal life by leveraging our shared services, such as guest relations and accounting.
Be part of the Casiola community
Learn from the best and share your expertise from Panama with our partner community.




Starting a vacation rental company in Panama
Opportunities in the Panama vacation rental market
Panama is fast becoming a favorite for international travelers, digital nomads, and expats seeking a destination that offers both adventure and sophistication. Guests can spend the morning exploring the historic charm of Casco Viejo, the afternoon relaxing on the San Blas Islands, and the evening dining in upscale Panama City. Popular areas like El Cangrejo, Boquete, Bocas del Toro, and the Pearl Islands offer a wide variety of travel experiences—and travelers want private, stylish, well-located vacation homes to match. With a growing focus on boutique tourism, travelers are turning away from traditional hotels and toward vacation rentals that deliver more space, local flavor, and personal comfort. As a Casiola franchisee, your property will benefit from expert marketing, dynamic pricing, 24/7 guest support, and full operations management, helping you thrive in this booming, diverse market.
Business opportunities
Business opportunities in the Panama vacation rental market
Panama’s vacation rental market is rich with investment opportunity, from its steady flow of tourists and business travelers to its growing remote work community. Real estate is still affordable in many key areas, yet demand is rising thanks to expanding flight routes, a strong expat population, and government support for tourism. Short-term rentals in destinations like Panama City, Boquete, and Bocas del Toro consistently perform well, especially when paired with great service, strong amenities, and local charm. With Casiola’s full-service franchise model, you’ll have access to powerful marketing, booking technology, local operations, and back-office support to run a scalable, efficient, and guest-loved business from day one.
Why Panama is perfect for a Casiola franchise
Panama is one of the most well-connected, business-friendly, and tourism-ready destinations in Latin America. From its world-famous Panama Canal to its modern infrastructure and breathtaking biodiversity, it offers something for every traveler. It’s also one of the few countries where you can start your day in a luxury high-rise and finish it surfing a Pacific wave or relaxing in the Caribbean. As a Casiola franchisee, you’ll offer guests a professionally managed, 5-star rental experience in any setting, while we handle the heavy lifting: cleaning, maintenance, linens, guest messaging, and pricing. Whether you own a sleek condo in Panama City or a beachfront villa on the Pacific Coast, Casiola gives you the tools, systems, and brand to stand out and scale in a competitive, opportunity-rich market.
Territory highlights
Territory highlights for your future guests
Guests visiting Panama are in for an unforgettable journey through diverse landscapes, vibrant cultures, and rich history. They can walk the historic streets of Casco Viejo, tour the engineering marvel of the Panama Canal, explore indigenous villages, or hike through cloud forests in Boquete. Sunseekers will love the white sands of the San Blas Islands, while adventure lovers can zipline in El Valle de Antón or surf in Santa Catalina. The country’s warm hospitality and modern comforts make it ideal for long stays and repeat visits. As a Casiola host, you’ll provide guests with a beautifully maintained, fully serviced home base to enjoy it all, while you grow a vacation rental business in one of Latin America’s most exciting and promising destinations.